NPEC-caged-dopamine

Cat. No. 3992

NPEC-caged-dopamine C17H18N2O6 [1257326-23-0]

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Chemical Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine

Biological Activity

NPEC ((N)-1-(2-nitrophenyl)ethyl) caged version of dopamine (Cat. No 3548); releases dopamine leading to D1 receptor activation upon UV light illumination (360 nm). Induces PKA activation and c-Fos expression in cortical and striatal neurons, with striatal neurons demonstrating a significantly greater detection and sensitivity to sub-second dopamine signals as compared to cortical neurons.

Technical Data

M.Wt:
346.33
Formula:
C17H18N2O6
Solubility:
Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
1257326-23-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Castro et al (2013) Striatal neurones have a specific ability to respond to phasic dopamine release. J.Physiol. [Epub ahead of print]. PMID: 23551948.

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Keywords: NPEC-caged-dopamine, supplier, caged, dopamine, compounds, neurotransmitters, D, receptors, dopaminergic, Tocris Bioscience, Non-selective Dopamine Agonist products

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