Cat. No. 3154

DL-Dithiothreitol C4H10O2S2 [3483-12-3]

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Alternative Names: DTT, Cleland's reagent, Sputolysin

Chemical Name: threo-1,4-Dimercapto-2,3-butanediol

Biological Activity

Reagent for maintaining SH groups in the reduced state.

Technical Data

Soluble to 100 mM in water
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Jabusch et al (1978) The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 91 532. PMID: 9762140.

Regg and Rudinger (1977) Reductive cleavage of cystine disulfides with tributylphosphine. Methods Enzymol. 47 111. PMID: 927167.

Sears et al (1977) Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 16 2031. PMID: 403938.

Cleland (1964) Dithiothreitol, a new protective group for SH groups. Biochemistry 3 480. PMID: 14192894.

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Keywords: DL-Dithiothreitol, supplier, Maintains, SH, groups, reduced, state, Reagents, Clelands, reagent, Tocris Bioscience, Biochemicals and Molecular Biology products

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