Cat. No. 3154

DL-Dithiothreitol C4H10O2S2 [3483-12-3]

Price and Availability

For DL-Dithiothreitol pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Names: DTT, Cleland's reagent, Sputolysin

Chemical Name: threo-1,4-Dimercapto-2,3-butanediol

Biological Activity

Reagent for maintaining SH groups in the reduced state.

Technical Data

Soluble to 100 mM in water
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

Jabusch et al (1978) The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 91 532. PMID: 9762140.

Regg and Rudinger (1977) Reductive cleavage of cystine disulfides with tributylphosphine. Methods Enzymol. 47 111. PMID: 927167.

Sears et al (1977) Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 16 2031. PMID: 403938.

Cleland (1964) Dithiothreitol, a new protective group for SH groups. Biochemistry 3 480. PMID: 14192894.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses DL-Dithiothreitol from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: DL-Dithiothreitol, supplier, Maintains, SH, groups, reduced, state, Reagents, Clelands, reagent, Tocris Bioscience, Biochemicals and Molecular Biology products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Spring/Summer 2016)

Our New Product guide highlights over 110 new products added in the first half of 2016. View PDF today.

divider line

New Products in this Area


Zwitterionic detergent


Click-activated fluorescent probe

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.