Cat. No. 3154
Alternative Names: DTT, Cleland's reagent, Sputolysin
Chemical Name: threo-1,4-Dimercapto-2,3-butanediol
Biological ActivityReagent for maintaining SH groups in the reduced state.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Jabusch et al (1978) The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 91 532. PMID: 9762140.
Rüegg and Rudinger (1977) Reductive cleavage of cystine disulfides with tributylphosphine. Methods Enzymol. 47 111. PMID: 927167.
Sears et al (1977) Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 16 2031. PMID: 403938.
Cleland (1964) Dithiothreitol, a new protective group for SH groups. Biochemistry 3 480. PMID: 14192894.
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Keywords: DL-Dithiothreitol, supplier, Maintains, SH, groups, reduced, state, Reagents, Clelands, reagent, Tocris Bioscience, Biochemicals and Molecular Biology products
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