Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
This peptide is supplied in gross weight.
Sold under licence from UNIL under the licenced patents
(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water with gentle warming|
References are publications that support the biological activity of the product.
Rebeaud et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 9 272 PMID: 18264101
If you know of a relevant reference for Z-VRPR-FMK trifluoroacetate salt, please let us know.
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Keywords: Z-VRPR-FMK trifluoroacetate salt, Z-VRPR-FMK trifluoroacetate salt supplier, MALT1, inhibitors, inhibits, NFKB, NFKappaB, NFκB, paracaspase, lymphomagenesis, ZVRPRFMK, Other, Proteases, 4645, Tocris Bioscience
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