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Discontinued ProductZ-IETD-FMK (Cat. No. 2170) has been withdrawn from sale for commercial reasons.
Biological Activity for Z-IETD-FMK
Inhibitor of caspase-8. Blocks TNFα-induced cytochrome c release and apoptosis in human leukemic U937 cells. Also inhibits nuclear protein cleavage in Jurkat, MCF-7 and HeLa cells in vitro.
Technical Data for Z-IETD-FMK
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Z-IETD-FMK
References for Z-IETD-FMK
References are publications that support the biological activity of the product.
Taimen and Kallajoki (2003) NuMA and nuclear lamins behave differently in Fas-mediated apoptosis. J.Cell Sci. 116 571 PMID: 12508117
Bang et al (2004) Differential response of MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents. Biochem.Pharmacol. 68 659 PMID: 15276073
Partheniou et al (2001) c-IAP1 blocks TNFα-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells. Biochem.Biophys.Res.Comm. 287 181
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Keywords: Z-IETD-FMK, Z-IETD-FMK supplier, Caspases, 2170, Tocris Bioscience
Citations for Z-IETD-FMK
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Currently there are no citations for Z-IETD-FMK.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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