WS 3

Discontinued Product

WS 3 (Cat. No. 2927) has been withdrawn from sale for commercial reasons.
Description: TRPM8 agonist; cooling agent
Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
Purity: ≥99% (HPLC)

Biological Activity for WS 3

WS 3 is a cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).

Technical Data for WS 3

M. Wt 211.34
Formula C13H25NO
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 39711-79-0
PubChem ID 62907
Smiles CC1CC(C(NCC)=O)C(C(C)C)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for WS 3

References are publications that support the biological activity of the product.

Behrendt et al (2004) Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br.J.Pharmacol. 141 737 PMID: 14757700

Bodding (2007) TRP proteins and cancer. Cell Signal. 19 617 PMID: 17029734

Rovner (2007) Better than mint. C&EN 85 95

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Keywords: WS 3, WS 3 supplier, TRPM8, agonists, cooling, agent, Channels, Transient, Receptor, Potential, WS3, TRPM, 2927, Tocris Bioscience

Citations for WS 3

Citations are publications that use Tocris products.

Currently there are no citations for WS 3.

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