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Biological Activity for UFP 112
Potent agonist for the nociceptin/orphanin FQ receptor, NOP (ORL1). Displays approximately 100-fold higher potency than N/OFQ and produces longer lasting effects on nociception and locomotor activity in mice. Induces a significant decrease in voluntary ethanol intake in msP rats.
Technical Data for UFP 112
|Desiccate at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for UFP 112
References for UFP 112
References are publications that support the biological activity of the product.
Economidou et al (2006) Effect of novel nociceptin/orphanin FQ-NOP receptor ligands on ethanol drinking in alcohol-preferring msP rats. Peptides 27 3299 PMID: 17097763
Rizzi et al (2006) UFP-112, a novel potent and selective peptide agonist for nociceptin/orphanin FQ receptors: in vitro and in vivo studies. Soc.Neurosci.Abstr. 789 16
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Keywords: UFP 112, UFP 112 supplier, nociceptin, orphanin, FQ, receptor, NOP, ORL1, agonist, Receptors, 2526, Tocris Bioscience
Citations for UFP 112
Citations are publications that use Tocris products.
Currently there are no citations for UFP 112.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.