UAMC 00039 dihydrochloride
Potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 μM, respectively). Orally available.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 382.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.61 mL||13.06 mL||26.13 mL|
|5 mM||0.52 mL||2.61 mL||5.23 mL|
|10 mM||0.26 mL||1.31 mL||2.61 mL|
|50 mM||0.05 mL||0.26 mL||0.52 mL|
References are publications that support the biological activity of the product.
Van Goethem et al (2011) Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? J.Med.Chem. 54 5737 PMID: 21711053
Maes et al (2007) Dipeptidyl peptidase 8/9-like activity in human leukocytes. J.Leukoc.Biol. 81 1252 PMID: 17287297
If you know of a relevant reference for UAMC 00039 dihydrochloride, please let us know.
View Related Products by Product Action
Keywords: UAMC 00039 dihydrochloride, UAMC 00039 dihydrochloride supplier, UAMC00039, dihydrochloride, dipeptidyl, peptidase, II, DPP-II, 2, inhibitors, inhibits, selective, potent, proteases, Other, Proteases, 4954, Tocris Bioscience
Citations for UAMC 00039 dihydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for UAMC 00039 dihydrochloride. Do you know of a great paper that uses UAMC 00039 dihydrochloride from Tocris? Please let us know.
Reviews for UAMC 00039 dihydrochloride
There are currently no reviews for this product. Be the first to review UAMC 00039 dihydrochloride and earn rewards!
Have you used UAMC 00039 dihydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Spring/Summer 2018)
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells