You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Tyrphostin B44, (-) enantiomer
Discontinued ProductTyrphostin B44, (-) enantiomer (Cat. No. 0578) has been withdrawn from sale for commercial reasons.
Biological Activity for Tyrphostin B44, (-) enantiomer
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer. Selective over ErbB2.
(+)-enantiomer also available.
Technical Data for Tyrphostin B44, (-) enantiomer
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tyrphostin B44, (-) enantiomer
References for Tyrphostin B44, (-) enantiomer
References are publications that support the biological activity of the product.
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896 PMID: 1676428
View Related Products by Target
View Related Products by Product Action
Keywords: Tyrphostin B44, (-) enantiomer, Tyrphostin B44, (-) enantiomer supplier, EGFR, kinase, inhibitors, inhibits, Epidermal, Growth, Factor, Receptors, ErbB, Her, RTK, Receptor, Tyrosine, Kinases, RTKs, (-)-TyrphostinB44, 0578, Tocris Bioscience
Citations for Tyrphostin B44, (-) enantiomer
Citations are publications that use Tocris products.
Currently there are no citations for Tyrphostin B44, (-) enantiomer.
Reviews for Tyrphostin B44, (-) enantiomer
There are currently no reviews for this product. Be the first to review Tyrphostin B44, (-) enantiomer and earn rewards!
Have you used Tyrphostin B44, (-) enantiomer?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.