Tropanyl 2-phenylthiobutanoate oxalate
Discontinued ProductTropanyl 2-phenylthiobutanoate oxalate (Cat. No. 0739) has been withdrawn from sale for commercial reasons.
Potent analgesic and nootropic agent. Causes increased release of acetylcholine at central muscarinic synapses.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
References are publications that support the biological activity of the product.
Gualtieri et al (1994) Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic acid esters. J.Med.Chem. 37 1712 PMID: 8201606
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Keywords: Tropanyl 2-phenylthiobutanoate oxalate, Tropanyl 2-phenylthiobutanoate oxalate supplier, SM32, Other, Acetylcholine, Non-selective, Muscarinics, 0739, Tocris Bioscience
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.