Tropanyl 2-phenylthiobutanoate oxalate
Discontinued ProductUnfortunately Tropanyl 2-phenylthiobutanoate oxalate (Cat. No. 0739) has been withdrawn from sale for commercial reasons.
Potent analgesic and nootropic agent. Causes increased release of acetylcholine at central muscarinic synapses.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 409.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.44 mL||12.21 mL||24.42 mL|
|5 mM||0.49 mL||2.44 mL||4.88 mL|
|10 mM||0.24 mL||1.22 mL||2.44 mL|
|50 mM||0.05 mL||0.24 mL||0.49 mL|
References are publications that support the products' biological activity.
Gualtieri et al (1994) Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic acid esters. J.Med.Chem. 37 1712 PMID: 8201606
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Keywords: Tropanyl 2-phenylthiobutanoate oxalate, supplier, SM32, Other, Acetylcholine, Non-selective, Muscarinics, Other, Acetylcholine, Tocris Bioscience
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Literature in this Area
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.