You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Analog of Fumagillin (Cat. No. 1768) that displays potent antiangiogenic activity in vitro and in vivo. Inhibits methionine aminopeptidase type II (MetAP2). Potently inhibits the proliferation of endothelial cells.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Arico-Muendel et al (2009) Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2. J.Med.Chem. 52 8047 PMID: 19929003
Huang et al (2003) TNP-470 promotes initial vascular sprouting in xenograft tumors. Mol.Cancer Ther. 3 335
Miura et al (2004) Carcinosarcoma-induced endothelial cells tube formation through KDR/FLK-1 is blocked by TNP-470. Cancer Letts. 203 45
Hines et al (2010) Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides. J.Pharm.Exp.Ther. 334 729
View Related Products by Product Action
Keywords: TNP 470, TNP 470 supplier, TNP470, methionine, aminopeptidase-2, MetAP2, proteases, proteinases, antiangiogenics, angiogenesis, AGM1470, AGM, 1470, Aminopeptidases, Antiangiogenics, 3750, Tocris Bioscience
Citations for TNP 470
Citations are publications that use Tocris products.
Currently there are no citations for TNP 470.
Reviews for TNP 470
There are currently no reviews for this product. Be the first to review TNP 470 and earn rewards!
Have you used TNP 470?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells