Tetrindole mesylate

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Cat.No. 0723 - Tetrindole mesylate | C20H26N2.CH3SO3H | CAS No. 170964-68-8
Description: MAO-A inhibitor
Chemical Name: 2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole mesylate
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Novel antidepressant, a selective inhibitor of MAO-A.

Compound Libraries

Tetrindole mesylate is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 390.54
Formula C20H26N2.CH3SO3H
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 170964-68-8
PubChem ID 54792409
InChI Key CWPNPYVNPOAMHY-UHFFFAOYSA-N
Smiles CS(O)(=O)=O.C1CCC(CC1)C1=CC=C2N3CCNC4CCCC(=C34)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.05 100

Preparing Stock Solutions

The following data is based on the product molecular weight 390.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.56 mL 12.8 mL 25.61 mL
5 mM 0.51 mL 2.56 mL 5.12 mL
10 mM 0.26 mL 1.28 mL 2.56 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Bos et al (1995) Resolution, EPC-syntheses, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the MAO-A inhibitor tetrindole hydrochloride. Arch.Pharm. (Wenheim) 328 619 PMID: 7492268

Korshunov et al (2000) Hemodynamic effects of tetrindol in alert normotensive mice and rats after blockade of nitric oxide synthesis. Bull.Exp.Biol.Med. 130 777 PMID: 11177242

Medvedev et al (1994) Monoamine oxidase inhibition by novel antidepressant tetrindole. Biochem.Pharmacol. 47 303 PMID: 8304974


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Citations for Tetrindole mesylate

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