Tertiapin LQ

Discontinued Product

Tertiapin LQ (Cat. No. 4339) has been withdrawn from sale for commercial reasons.
Description: Selective Kir1.1 blocker; derivative of tertiapin-Q (Cat. No. 1316)

Biological Activity for Tertiapin LQ

Tertiapin LQ is a blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316).

Technical Data for Tertiapin LQ

M. Wt 2428.03
Formula C106H179N33O24S4

(Modifications: Disulfide bridge between 3 - 14, 5 - 18, Lys-21 = C-terminal amide)

Storage Store at -20°C
PubChem ID 90488935
Smiles [H]N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CNC4=C3C=CC=C4)NC2=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Tertiapin LQ

Certificate of Analysis / Product Datasheet
Select another batch:

References for Tertiapin LQ

References are publications that support the biological activity of the product.

Ramu et al (2008) Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc.Natl.Acad.Sci.USA 105 10774 PMID: 18669667

View Related Products by Product Action

View all Inward Rectifier Potassium (Kir) Channel Blockers

Keywords: Tertiapin LQ, Tertiapin LQ supplier, TertiapinLQ, kir1.1, blockers, selective, venoms, inward, rectifier, potassium, channels, Inward, Potassium, Channels, 4339, Tocris Bioscience

Citations for Tertiapin LQ

Citations are publications that use Tocris products.

Currently there are no citations for Tertiapin LQ.

Reviews for Tertiapin LQ

There are currently no reviews for this product. Be the first to review Tertiapin LQ and earn rewards!

Have you used Tertiapin LQ?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review