Synthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO and in ethanol|
Preparing Stock Solutions
The following data is based on the product molecular weight 416.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.4 mL||12 mL||24 mL|
|5 mM||0.48 mL||2.4 mL||4.8 mL|
|10 mM||0.24 mL||1.2 mL||2.4 mL|
|50 mM||0.05 mL||0.24 mL||0.48 mL|
References are publications that support the biological activity of the product.
Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226 PMID: 11464105
Rostowska-Nadolska et al (2010) Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86 PMID: 20439185
If you know of a relevant reference for Tacalcitol, please let us know.
Keywords: Tacalcitol, Tacalcitol supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Vitamin, D, Receptors, Immunosuppressants, 4157, Tocris Bioscience
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