Tacalcitol

Pricing Availability Delivery Time Qty
Cat.No. 4157 - Tacalcitol | C27H44O3 | CAS No. 57333-96-7
Description: Synthetic vitamin D3 (Cat. No. 4156) analog
Chemical Name: (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Synthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.

Technical Data

M. Wt 416.64
Formula C27H44O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 57333-96-7
PubChem ID 5283734
InChI Key BJYLYJCXYAMOFT-RSFVBTMBSA-N
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CC[C@@H](O)C(C)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble in DMSO and in ethanol

Preparing Stock Solutions

The following data is based on the product molecular weight 416.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.4 mL 12 mL 24 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
10 mM 0.24 mL 1.2 mL 2.4 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References

References are publications that support the biological activity of the product.

Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226 PMID: 11464105

Rostowska-Nadolska et al (2010) Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86 PMID: 20439185


If you know of a relevant reference for Tacalcitol, please let us know.

View Related Products by Target

Keywords: Tacalcitol, Tacalcitol supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Vitamin, D, Receptors, Immunosuppressants, 4157, Tocris Bioscience

Citations for Tacalcitol

Citations are publications that use Tocris products.

Currently there are no citations for Tacalcitol. Do you know of a great paper that uses Tacalcitol from Tocris? Please let us know.

Reviews for Tacalcitol

There are currently no reviews for this product. Be the first to review Tacalcitol and earn rewards!

Have you used Tacalcitol?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
  • Retinoic Acid Receptors
  • Retinoid X Receptors
  • Vitamin D Receptors