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Cat.No. 4157 - Tacalcitol | C27H44O3 | CAS No. 57333-96-7
Description: Synthetic vitamin D3 (Cat. No. 4156) analog
Chemical Name: (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
Purity: ≥98% (HPLC)
Literature (2)

Biological Activity

Synthetic vitamin D3 (Cat. No. 4156) analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.

Technical Data

M. Wt 416.64
Formula C27H44O3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 57333-96-7
PubChem ID 5283734
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CC[C@@H](O)C(C)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble in DMSO and in ethanol

Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Fukuoka et al (2001) Tacalcitol, an active vitamin D3, induces nerve growth factor in human epidermal keratinocytes. Skin Pharmacol.Appl.Skin Physiol. 14 226 PMID: 11464105

Rostowska-Nadolska et al (2010) Vitamin D derivatives: calci. and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. 55 86 PMID: 20439185

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Keywords: Tacalcitol, Tacalcitol supplier, Tacalcitol, VDR, receptor, vitamin, D3, calcitrol, analogue, bone, Vitamin, D, Receptors, Immunosuppressants, 4157, Tocris Bioscience

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