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Vitamin D3

Cat. No. 4156 2 Citations Submit a Review Datasheet / COA / SDS
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Cat.No. 4156 - Vitamin D3 | C27H44O | CAS No. 67-97-0
Description: Precursor of calcifediol (Cat. No. 4036). Naturally occurring form of vitamin D
Alternative Names: Cholecalciferol
Chemical Name: 9,10-Secocholesta-5,7,10(19)-trien-3β-ol
Purity: ≥98% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (2)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Precursor of calcifediol (Cat. No. 4036). Naturally occurring form of vitamin D; predominantly active form found in humans.

Technical Data

M. Wt 384.64
Formula C27H44O
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 67-97-0
PubChem ID 5280795
InChI Key QYSXJUFSXHHAJI-YRZJJWOYSA-N
Smiles C[C@@](CCC2)3[C@](CC[C@@H]3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)CC1)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 19.23 50
ethanol 38.46 100

Preparing Stock Solutions

The following data is based on the product molecular weight 384.64. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.6 mL 13 mL 26 mL
5 mM 0.52 mL 2.6 mL 5.2 mL
10 mM 0.26 mL 1.3 mL 2.6 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the biological activity of the product.

Welsh et al (2003) Vitamin D-3 receptor as a target for breast cancer prevention. J.Nutr. 133 2425S PMID: 12840219

Lane (2010) Vitamin D and systemic lupus erythematosus: bones, muscles, and joints. Curr.Rheumatol.Rep. 12 259 PMID: 20429045

If you know of a relevant reference for Vitamin D3, please let us know.

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Keywords: Vitamin D3, Vitamin D3 supplier, Vitamin, D3, cholecalciferol, VDR, receptors, agonists, precursors, naturally, occurring, active, vitamin, D, Cholecalciferol, Receptors, 4156, Tocris Bioscience

2 Citations for Vitamin D3

Citations are publications that use Tocris products. Selected citations for Vitamin D3 include:

Karadottir et al (2015) Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells. J Pharmacol Exp Ther 3 e1483 PMID: 26664810

Lu et al (2016) Generation of serotonin neurons from human pluripotent stem cells. Nat Biotechnol 34 89 PMID: 26655496

Do you know of a great paper that uses Vitamin D3 from Tocris? Please let us know.

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Literature in this Area

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