Vitamin D3
Biological Activity
Precursor of calcifediol (Cat. No. 4036). Naturally occurring form of vitamin D; predominantly active form found in humans.
Technical Data
| M. Wt | 384.64 |
| Formula | C27H44O |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 67-97-0 |
| PubChem ID | 5280795 |
| InChI Key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| Smiles | C[C@@](CCC2)3[C@](CC[C@@H]3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)CC1)\C1=C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.23 | 50 | |
| ethanol | 38.46 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 384.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.6 mL | 13 mL | 26 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.2 mL |
| 10 mM | 0.26 mL | 1.3 mL | 2.6 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.52 mL |
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Product Datasheets
References
References are publications that support the biological activity of the product.
Welsh et al (2003) Vitamin D-3 receptor as a target for breast cancer prevention. J.Nutr. 133 2425S PMID: 12840219
Lane (2010) Vitamin D and systemic lupus erythematosus: bones, muscles, and joints. Curr.Rheumatol.Rep. 12 259 PMID: 20429045
If you know of a relevant reference for Vitamin D3, please let us know.
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2 Citations for Vitamin D3
Citations are publications that use Tocris products. Selected citations for Vitamin D3 include:
Karadottir et al (2015) Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells. J Pharmacol Exp Ther 3 e1483 PMID: 26664810
Lu et al (2016) Generation of serotonin neurons from human pluripotent stem cells. Nat Biotechnol 34 89 PMID: 26655496
Do you know of a great paper that uses Vitamin D3 from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:
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