Vitamin D3

Pricing Availability Delivery Time Qty
Cat.No. 4156 - Vitamin D3 | C27H44O | CAS No. 67-97-0
Description: Precursor of calcifediol (Cat. No. 4036). Naturally occurring form of vitamin D
Alternative Names: Cholecalciferol
Chemical Name: 9,10-Secocholesta-5,7,10(19)-trien-3β-ol
Purity: ≥98% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Precursor of calcifediol (Cat. No. 4036). Naturally occurring form of vitamin D; predominantly active form found in humans.

Technical Data

M. Wt 384.64
Formula C27H44O
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 67-97-0
PubChem ID 5280795
InChI Key QYSXJUFSXHHAJI-YRZJJWOYSA-N
Smiles C[C@@](CCC2)3[C@](CC[C@@H]3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)CC1)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 19.23 50
ethanol 38.46 100

Preparing Stock Solutions

The following data is based on the product molecular weight 384.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.6 mL 13 mL 26 mL
5 mM 0.52 mL 2.6 mL 5.2 mL
10 mM 0.26 mL 1.3 mL 2.6 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Welsh et al (2003) Vitamin D-3 receptor as a target for breast cancer prevention. J.Nutr. 133 2425S PMID: 12840219

Lane (2010) Vitamin D and systemic lupus erythematosus: bones, muscles, and joints. Curr.Rheumatol.Rep. 12 259 PMID: 20429045


If you know of a relevant reference for Vitamin D3, please let us know.

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Keywords: Vitamin D3, supplier, Vitamin, D3, cholecalciferol, VDR, receptors, agonists, precursors, naturally, occurring, active, vitamin, D, Cholecalciferol, Vitamin, D, Receptors, Tocris Bioscience

2 Citations for Vitamin D3

Citations are publications that use Tocris products. Selected citations for Vitamin D3 include:

Lu et al (2016) Generation of serotonin neurons from human pluripotent stem cells. Nat Biotechnol 34 89 PMID: 26655496

Karadottir et al (2015) Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells. J Pharmacol Exp Ther 3 e1483 PMID: 26664810


Do you know of a great paper that uses Vitamin D3 from Tocris? If so please let us know.

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Reviews

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Literature in this Area

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Pathways for Vitamin D3

Protocols

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