Discontinued Product

StRIP16 (Cat. No. 6575) has been withdrawn from sale for commercial reasons.
Description: Rab8a GTPase-binding stapled peptide

Biological Activity for StRIP16

StRIP16 is a rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.

Technical Data for StRIP16

M. Wt 2300.61
Formula C116H154N24O26

(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)

Storage Store at -20°C
Smiles CC(C[C@@H](C(N[C@]1(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)CC(N)=O)=O)(C(N[C@H](C(N)=O)C(C)C)=O)C)C)=O)NC([C@@H](NC([C@@H](NC([C@@]4(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N4)=O)CC5=CC=CC=C5)=O)CC6=CNC7=CC=CC=C67)=O)CCC(N)=O)=O)C)C)=O)CC8=CC=C(C=C8)O)=O)CC9=CN=CN9)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for StRIP16

References are publications that support the biological activity of the product.

Cromm et al (2016) Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chem.Biol. 11 2375 PMID: 27336832

Keywords: StRIP16, StRIP16 supplier, RAb8a, binding, stapled, peptides, GTPase, binds, cell-permeable, Other, Small, Monomeric, GTPases, Stapled, Peptides, 6575, Tocris Bioscience

Citations for StRIP16

Citations are publications that use Tocris products.

Currently there are no citations for StRIP16.

Reviews for StRIP16

There are currently no reviews for this product. Be the first to review StRIP16 and earn rewards!

Have you used StRIP16?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review