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Biological Activity for SN 2
SN 2 is a selective TRPML3 channel activator (EC50 = 1.13 μM).
Compound Libraries for SN 2
Technical Data for SN 2
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SN 2
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for SN 2
The following data is based on the product molecular weight 255.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.92 mL||19.58 mL||39.16 mL|
|5 mM||0.78 mL||3.92 mL||7.83 mL|
|10 mM||0.39 mL||1.96 mL||3.92 mL|
|50 mM||0.08 mL||0.39 mL||0.78 mL|
References for SN 2
References are publications that support the biological activity of the product.
Grimm et al (2010) Small molecule activators of TRPML3. Chem.Biol. 17 135 PMID: 20189104
Jörs (2010) Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice. PLoS ONE 5 e14317 PMID: 21179200
If you know of a relevant reference for SN 2, please let us know.
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Keywords: SN 2, SN 2 supplier, Selective, TRPML3, channels, activators, SN2, transient, receptor, potential, activates, TRPML, 4907, Tocris Bioscience
Citations for SN 2
Citations are publications that use Tocris products.
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Reviews for SN 2
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Literature in this Area
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