You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).
Please note - unpublished, in-house data suggests SBP1 has approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.
(Modifications: Ile-1 = FITC-PEG4-Ile, Ser-23 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in 0.1M PBS (pH 7.4)|
References are publications that support the biological activity of the product.
Zhang et al (2020) The first-in-class peptide binder to the SARS-CoV-2 spike protein. BioRxiv - Paper not yet peer reviewed.
If you know of a relevant reference for SBP1-FITC, please let us know.
View Related Products by Target
Keywords: SBP1-FITC SBP1-FITC, SBP1-FITC SBP1-FITC supplier, spike, binding, protein, SARS-CoV-2, receptor, domain, RBD, COVID-19, severe, acute, respiratory, syndrome, ACE2, peptide, fluorescently-labeled, flluorescence, Enzyme, Probes, and, Substrates, 7232, Tocris Bioscience
Citations for SBP1-FITC
Citations are publications that use Tocris products.
Currently there are no citations for SBP1-FITC. Do you know of a great paper that uses SBP1-FITC from Tocris? Please let us know.
Reviews for SBP1-FITC
There are currently no reviews for this product. Be the first to review SBP1-FITC and earn rewards!
Have you used SBP1-FITC?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image