SBP1

Pricing Availability   Qty
Cat.No. 7233 - SBP1 | Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-Tyr-Gln-Ser-NH2
Description: ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (1)

Biological Activity

Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (Kd = 1.3 μM in biochemical assay).

Technical Data

M. Wt 2802.05
Formula C127H185N31O41
Sequence IEEQAKTFLDKFNHEAEDLFYQS

(Modifications: Ser-23 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
InChI Key VTVUOJBJFPPIBF-SDBILGLNSA-N
Smiles O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in PBS

References

References are publications that support the biological activity of the product.

Zhang et al (2020) Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD. BioRxiv - Paper not yet peer reviewed


If you know of a relevant reference for SBP1, please let us know.

Keywords: SBP1, SBP1 supplier, spike, binding, protein, SARS-CoV-2, receptor, domain, RBD, COVID-19, severe, acute, respiratory, syndrome, ACE2, peptide, fluorescent, FITC, Antivirals, 7233, Tocris Bioscience

Citations for SBP1

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Literature in this Area

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