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RuBi-Nicotine is a ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.
Sold under licence from Columbia University
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 808.81. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||2.47 mL||12.36 mL||24.73 mL|
|2.5 mM||0.49 mL||2.47 mL||4.95 mL|
|5 mM||0.25 mL||1.24 mL||2.47 mL|
|25 mM||0.05 mL||0.25 mL||0.49 mL|
References are publications that support the biological activity of the product.
Filevich et al (2010) A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 104 1248 PMID: 20825994
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