RuBi-Dopa

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Cat.No. 4932 - RuBi-Dopa | C31H36Cl2N5O2PRu
Description: Caged dopamine; exhibits two-photon sensitivity
Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-(3,4-Dihydroxyphenyl)ethylamino ruthenium(2+) dichloride complex
Datasheet
Citations
Literature

Biological Activity

RuBi-caged dopamine (Cat. No. 3548); exhibits two-photon sensitivity. Enables non-invasive, optical activation of dopamine receptors with the spatial resolution of a single dendritic spine. Does not display phototoxicity at a concentration of 300 μM.

Licensing Information

Sold under licence from Columbia University

Technical Data

M. Wt 713.6
Formula C31H36Cl2N5O2PRu
Storage Store at -20°C
PubChem ID 90488992
InChI Key FPJFHIJODNWCIM-UHFFFAOYSA-L
Smiles [Cl-].[Cl-].[Ru++].CP(C)C.NCCC1=CC=C(O)C(O)=C1.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 14.27 20

Preparing Stock Solutions

The following data is based on the product molecular weight 713.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.4 mL 7.01 mL 14.01 mL
5 mM 0.28 mL 1.4 mL 2.8 mL
10 mM 0.14 mL 0.7 mL 1.4 mL
50 mM 0.03 mL 0.14 mL 0.28 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Araya et al (2013) Two-photon optical interrogation of individual dendritic spines with caged dopamine. ACS Chem. Neurosci. [Epub ahead of print] PMID: 23672485


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Keywords: caged dopamine two photon sensitive sensitivity microscopy dopaminergic neurons high resolution dendritic spines Non-selective Dopamine

Citations for RuBi-Dopa

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Dopamine Receptors

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Pathways for RuBi-Dopa

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