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Discontinued Product
RuBi-4AP (Cat. No. 3557) has been withdrawn from sale for commercial reasons.
Description: Caged 4-aminopyridine; a non-selective KV channel blocker
Alternative Names: Rubi-4-aminopyridine
Chemical Name: bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex
Biological Activity
Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.
Licensing Information
Sold under licence from Columbia University
Technical Data
| M. Wt | 672.58 |
| Formula | C30H28Cl2N8Ru |
| Storage | Store at -20°C |
| CAS Number | 851956-02-0 |
| PubChem ID | 11422486 |
| InChI Key | MVEGPXUCOGNVKR-UHFFFAOYSA-L |
| Smiles | [Cl-].[Cl-].[Ru++].NC1=CC=NC=C1.NC1=CC=NC=C1.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882 PMID: 12537482
Nikolenko et al (2005) Two-photon uncaging of neurochemicals using inorganic metal complexes. Chem.Commun. 13 1752
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Citations for RuBi-4AP
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Currently there are no citations for RuBi-4AP.
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