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RuBi-4AP

Cat. No. 3557 Submit a Review Datasheet / COA / SDS

Discontinued Product

RuBi-4AP (Cat. No. 3557) has been withdrawn from sale for commercial reasons.
Cat.No. 3557 - RuBi-4AP | C30H28Cl2N8Ru | CAS No. 851956-02-0
Description: Caged 4-aminopyridine; a non-selective KV channel blocker
Alternative Names: Rubi-4-aminopyridine
Chemical Name: bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex
Datasheet
Citations
Reviews
Literature (5)
Biological Activity Technical Data Datasheets References

Biological Activity

Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.

Licensing Information

Sold under licence from Columbia University

Technical Data

M. Wt 672.58
Formula C30H28Cl2N8Ru
Storage Store at -20°C
CAS Number 851956-02-0
PubChem ID 11422486
InChI Key MVEGPXUCOGNVKR-UHFFFAOYSA-L
Smiles [Cl-].[Cl-].[Ru++].NC1=CC=NC=C1.NC1=CC=NC=C1.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882 PMID: 12537482

Nikolenko et al (2005) Two-photon uncaging of neurochemicals using inorganic metal complexes. Chem.Commun. 13 1752

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Citations for RuBi-4AP

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