(RS)-3,4-DCPG

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Cat.No. 1394 - (RS)-3,4-DCPG | C10H9NO6 | CAS No. 176796-64-8
Description: Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
Chemical Name: (RS)-3,4-Dicarboxyphenylglycine
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG (Cat. No. 1302) or (R)-3,4,-DCPG (Cat. No. 1395).

Technical Data

M. Wt 239.18
Formula C10H9NO6
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 176796-64-8
PubChem ID 3313698
InChI Key IJVMOGKBEVRBPP-UHFFFAOYSA-N
Smiles NC(C(O)=O)C1=CC=C(C(O)=O)C(=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 50 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 239.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.18 mL 20.9 mL 41.81 mL
5 mM 0.84 mL 4.18 mL 8.36 mL
10 mM 0.42 mL 2.09 mL 4.18 mL
50 mM 0.08 mL 0.42 mL 0.84 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732 PMID: 11311902

Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111 PMID: 9455991

Thomas et al (1998) Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. Neuropharmacology 37 1223 PMID: 9849660


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Pathways for (RS)-3,4-DCPG

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