(R)-3,4-DCPG

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Cat.No. 1395 - (R)-3,4-DCPG | C10H9NO6 | CAS No. 201730-10-1
Description: AMPA antagonist/weak NMDA antagonist
Chemical Name: (R)-3,4-Dicarboxyphenylglycine
Purity: ≥96% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (5)

Biological Activity

AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors.

Racemate and S-enantiomer also available.

Technical Data

M. Wt 239.18
Formula C10H9NO6
Storage Desiccate at RT
Purity ≥96% (HPLC)
CAS Number 201730-10-1
PubChem ID 6604849
InChI Key IJVMOGKBEVRBPP-SSDOTTSWSA-N
Smiles N[C@@]([H])(C(O)=O)C1=CC(C(O)=O)=C(C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 100 mM in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732 PMID: 11311902

Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111 PMID: 9455991


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Keywords: (R)-3,4-DCPG, (R)-3,4-DCPG supplier, AMPA, antagonists, weak, NMDA, Glutamate, Ionotropic, Non-Selective, iGlur, Receptors, Non-selective, 1395, Tocris Bioscience

1 Citation for (R)-3,4-DCPG

Citations are publications that use Tocris products. Selected citations for (R)-3,4-DCPG include:

Sun et al (2012) Structure based model for the prediction of phospholipidosis induction potential of small molecules. J Chem Inf Model 52 1798 PMID: 22725677


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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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