(RS)-3,4,5-THPG

Discontinued Product

(RS)-3,4,5-THPG (Cat. No. 1012) has been withdrawn from sale for commercial reasons.
Description: mGlu6 antagonist
Chemical Name: (RS)-3,4,5-Trihydroxyphenylglycine
Datasheet
Citations
Reviews
Literature (4)

Biological Activity for (RS)-3,4,5-THPG

First antagonist of mGlu6, the group III mGlu receptor found in the retina.

Technical Data for (RS)-3,4,5-THPG

M. Wt 199.1636
Storage Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (RS)-3,4,5-THPG

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for (RS)-3,4,5-THPG

References are publications that support the biological activity of the product.

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

Thoreson et al (1997) Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmacology 36 1 PMID: 9144636

Keywords: (RS)-3,4,5-THPG, (RS)-3,4,5-THPG supplier, Glutamate, (Metabotropic), Group, III, Receptors, 1012, Tocris Bioscience

Citations for (RS)-3,4,5-THPG

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Currently there are no citations for (RS)-3,4,5-THPG.

Reviews for (RS)-3,4,5-THPG

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Learning & Memory Poster

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.