(RS)-3,4,5-THPG

Name: ( RS )-3,4,5-THPG
Brand: Tocris Bioscience
SKU: 1012

Cat. No. 1012 Submit a Review Datasheet / COA / SDS

Discontinued Product

(RS)-3,4,5-THPG (Cat. No. 1012) has been withdrawn from sale for commercial reasons.

Description: mGlu₆ antagonist

Chemical Name: (RS)-3,4,5-Trihydroxyphenylglycine

Datasheet

Citations

Reviews

Literature (8)

Biological Activity Technical Data Datasheets References

Biological Activity

First antagonist of mGlu₆, the group III mGlu receptor found in the retina.

Technical Data

M. Wt	199.1636
Storage	Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

Safety Datasheet

References

References are publications that support the biological activity of the product.

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

Thoreson et al (1997) Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmacology 36 1 PMID: 9144636

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Keywords: (RS)-3,4,5-THPG, (RS)-3,4,5-THPG supplier, Glutamate, (Metabotropic), Group, III, Receptors, 1012, Tocris Bioscience

Citations for (RS)-3,4,5-THPG

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Literature in this Area

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Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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