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Discontinued Product
1012 has been discontinued.
View all Glutamate (Metabotropic) Group III Receptors products.
Description: mGlu6 antagonist
Chemical Name: (RS)-3,4,5-Trihydroxyphenylglycine
Biological Activity for (RS)-3,4,5-THPG
First antagonist of mGlu6, the group III mGlu receptor found in the retina.
Technical Data for (RS)-3,4,5-THPG
| M. Wt | 199.1636 |
| Storage | Desiccate at -20°C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (RS)-3,4,5-THPG
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
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References for (RS)-3,4,5-THPG
References are publications that support the biological activity of the product.
Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745
Thoreson et al (1997) Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmacology 36 1 PMID: 9144636
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Keywords: (RS)-3,4,5-THPG, (RS)-3,4,5-THPG supplier, Glutamate, (Metabotropic), Group, III, Receptors, 1012, Tocris Bioscience
Citations for (RS)-3,4,5-THPG
Citations are publications that use Tocris products.
Currently there are no citations for (RS)-3,4,5-THPG.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
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