Chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 2 mg/ml in 20% acetonitrile / water|
References are publications that support the biological activity of the product.
Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770 PMID: 19380825
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Keywords: RETF-4NA, RETF-4NA supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Other, Proteases, Enzyme, Substrates, /, Activators, Non-selective, AT, Receptors, Angiotensin, 3841, Tocris Bioscience
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