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Chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 2 mg/ml in 20% acetonitrile / water|
References are publications that support the biological activity of the product.
Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770 PMID: 19380825
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Keywords: RETF-4NA, RETF-4NA supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Other, Proteases, Enzyme, Substrates, /, Activators, Non-selective, AT, Receptors, Angiotensin, 3841, Tocris Bioscience
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