Pricing Availability   Qty
Cat.No. 3841 - RETF-4NA | Ac-Arg-Glu-Thr-Phe-4-Nitroanilide | CAS No. 1160928-63-1
Description: Selective chymase substrate
Literature (1)

Biological Activity

Chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.

Technical Data

M. Wt 713.75
Formula C32H43N9O10
Sequence RETF

(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)

Storage Store at -20°C
CAS Number 1160928-63-1
PubChem ID 90488886
Smiles C[C@@H](O)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC1=CC=C(C=C1)[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 2 mg/ml in 20% acetonitrile / water

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:


References are publications that support the biological activity of the product.

Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770 PMID: 19380825

If you know of a relevant reference for RETF-4NA, please let us know.

View Related Products by Product Action

View all Other Protease Substrates

Keywords: RETF-4NA, RETF-4NA supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Other, Proteases, Enzyme, Substrates, /, Activators, Non-selective, AT, Receptors, Angiotensin, 3841, Tocris Bioscience

Citations for RETF-4NA

Citations are publications that use Tocris products.

Currently there are no citations for RETF-4NA. Do you know of a great paper that uses RETF-4NA from Tocris? Please let us know.

Reviews for RETF-4NA

There are currently no reviews for this product. Be the first to review RETF-4NA and earn rewards!

Have you used RETF-4NA?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

New Product Guide

New Product Guide [Spring/Summer 2019]

Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Chemogenetics
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells