(R)-(-)-Deprenyl hydrochloride

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Cat.No. 1095 - (R)-(-)-Deprenyl hydrochloride | C13H17N.HCl | CAS No. 14611-52-0
Description: MAO-B inhibitor
Alternative Names: Selegiline
Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Selective inhibitor of monoamine oxidase B (MAO-B).

Technical Data

M. Wt 223.74
Formula C13H17N.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 14611-52-0
PubChem ID 26758
InChI Key IYETZZCWLLUHIJ-UTONKHPSSA-N
Smiles C#CCN(C)[C@H](C)CC1=CC=CC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 22.37 100

Preparing Stock Solutions

The following data is based on the product molecular weight 223.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.47 mL 22.35 mL 44.69 mL
5 mM 0.89 mL 4.47 mL 8.94 mL
10 mM 0.45 mL 2.23 mL 4.47 mL
50 mM 0.09 mL 0.45 mL 0.89 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97 PMID: 1639115

Kaseda et al (1999) Effect of selegeline on dopamine concentration in the striatum of a primate. Brain Res. 815 44 PMID: 9974121

Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341 PMID: 9518683

Mercuri et al (1998) Modification of levodopa responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613 PMID: 9585355

Merck Index 12 8569


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Citations for (R)-(-)-Deprenyl hydrochloride

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Literature in this Area

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