(R)-(-)-Deprenyl hydrochloride

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Cat.No. 1095 - (R)-(-)-Deprenyl hydrochloride | C13H17N.HCl | CAS No. 14611-52-0
Description: MAO-B inhibitor
Alternative Names: Selegiline
Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for (R)-(-)-Deprenyl hydrochloride

(R)-(-)-Deprenyl hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B).

Technical Data for (R)-(-)-Deprenyl hydrochloride

M. Wt 223.74
Formula C13H17N.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 14611-52-0
PubChem ID 26758
Smiles C#CCN(C)[C@H](C)CC1=CC=CC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for (R)-(-)-Deprenyl hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
water 22.37 100

Preparing Stock Solutions for (R)-(-)-Deprenyl hydrochloride

The following data is based on the product molecular weight 223.74. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.47 mL 22.35 mL 44.69 mL
5 mM 0.89 mL 4.47 mL 8.94 mL
10 mM 0.45 mL 2.23 mL 4.47 mL
50 mM 0.09 mL 0.45 mL 0.89 mL

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Product Datasheets for (R)-(-)-Deprenyl hydrochloride

Certificate of Analysis / Product Datasheet
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References for (R)-(-)-Deprenyl hydrochloride

References are publications that support the biological activity of the product.

Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97 PMID: 1639115

Kaseda et al (1999) Effect of selegeline on DA concentration in the striatum of a primate. Brain Res. 815 44 PMID: 9974121

Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341 PMID: 9518683

Mercuri et al (1998) Modification of lev. responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613 PMID: 9585355

Merck Index 12 8569

If you know of a relevant reference for (R)-(-)-Deprenyl hydrochloride, please let us know.

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Citations for (R)-(-)-Deprenyl hydrochloride

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