Enantiomer of escitalopram oxalate (Cat. No. 1427). Postulated to allosterically modulate the affinity of the S-enantiomer.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 414.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.41 mL||12.06 mL||24.13 mL|
|5 mM||0.48 mL||2.41 mL||4.83 mL|
|10 mM||0.24 mL||1.21 mL||2.41 mL|
|50 mM||0.05 mL||0.24 mL||0.48 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Jacquot et al (2007) Escitalopram and citalopram: the unexpected role of the R-enantiomer. Encephale 33 179 PMID: 17675913
Sánchez et al (2006) The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic & Clinical Pharmacology & Toxicology 99 91 PMID: 16918708
If you know of a relevant reference for (R)-Citalopram oxalate, please let us know.
Keywords: Enantiomers escitalopram oxalate 5-HT reuptake modulators allosteric SERT 5-hydroxytryptamine monoamine neurotransmitters citalopram depression 5-HT Transporters
Citations for (R)-Citalopram oxalate
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Literature in this Area
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.