(R)-Citalopram oxalate

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Cat.No. 5763 - (R)-Citalopram oxalate | C20H21FN2O.C2H2O4 | CAS No. 219861-53-7
Description: Enantiomer of escitalopram oxalate (Cat. No. 1427)
Chemical Name: (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Enantiomer of escitalopram oxalate (Cat. No. 1427). Postulated to allosterically modulate the affinity of the S-enantiomer.

Technical Data

M. Wt 414.43
Formula C20H21FN2O.C2H2O4
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 219861-53-7
PubChem ID 45038690
InChI Key KTGRHKOEFSJQNS-VEIFNGETSA-N
Smiles FC(C=C3)=CC=C3[C@@]1(CCCN(C)C)OCC2=C1C=CC(C#N)=C2.OC(C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.44 100
water 20.72 50

Preparing Stock Solutions

The following data is based on the product molecular weight 414.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.41 mL 12.06 mL 24.13 mL
5 mM 0.48 mL 2.41 mL 4.83 mL
10 mM 0.24 mL 1.21 mL 2.41 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Jacquot et al (2007) Escitalopram and citalopram: the unexpected role of the R-enantiomer. Encephale 33 179 PMID: 17675913

Sánchez et al (2006) The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic & Clinical Pharmacology & Toxicology 99 91 PMID: 16918708


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Keywords: (R)-Citalopram oxalate, supplier, Enantiomers, escitalopram, oxalate, 5-HT, reuptake, modulators, allosteric, SERT, 5-hydroxytryptamine, monoamine, neurotransmitters, citalopram, depression, 5-HT, Transporters, 5-HT, Transporters, Tocris Bioscience

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