Discontinued Product

Unfortunately Quisqualamine (Cat. No. 0381) has been withdrawn from sale for commercial reasons.
Cat.No. 0381 - Quisqualamine | CAS No. 68373-11-5
Description: Weak GABAA agonist
Chemical Name: 3,5-Dioxo-1,2,4-oxadiazolidine-2-aminoethane

Biological Activity

The α-decarboxylated product of quisqualic acid; shows activity at GABAA receptors.

Technical Data

M. Wt 145.12
Storage Store at RT
CAS Number 68373-11-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 145.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.89 mL 34.45 mL 68.91 mL
5 mM 1.38 mL 6.89 mL 13.78 mL
10 mM 0.69 mL 3.45 mL 6.89 mL
50 mM 0.14 mL 0.69 mL 1.38 mL

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Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service.
Safety Datasheet


References are publications that support the products' biological activity.

Evans et al (1978) Quisqualamine, a novel GABA-related amino acid. J.Pharm.Pharmacol. 30 364 PMID: 26767

Blake et al (1993) Actions of Quisqualamine and homoquisqualamine in the neonatal rat spinal cord in vitro. J.Physiol. 459 479P PMID:

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Keywords: Quisqualamine, supplier, GABAA, Receptors, GABAA, Receptors, Tocris Bioscience

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.


Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.


Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.


Schizophrenia Poster

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.