Discontinued Product

Quisqualamine (Cat. No. 0381) has been withdrawn from sale for commercial reasons.
Description: Weak GABAA agonist
Chemical Name: 3,5-Dioxo-1,2,4-oxadiazolidine-2-aminoethane
Literature (7)

Biological Activity for Quisqualamine

The α-decarboxylated product of quisqualic acid; shows activity at GABAA receptors.

Technical Data for Quisqualamine

M. Wt 145.12
Storage Store at RT
CAS Number 68373-11-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Quisqualamine

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for Quisqualamine

References are publications that support the biological activity of the product.

Evans et al (1978) Quisqualamine, a novel GABA-related amino acid. J.Pharm.Pharmacol. 30 364 PMID: 26767

Blake et al (1993) Actions of Quisqualamine and homoquisqualamine in the neonatal rat spinal cord in vitro. J.Physiol. 459 479P

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Keywords: Quisqualamine, Quisqualamine supplier, GABAA, Receptors, 0381, Tocris Bioscience

Citations for Quisqualamine

Citations are publications that use Tocris products.

Currently there are no citations for Quisqualamine.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Ion Channel Product Listing

Ion Channel Product Listing

A collection of around 500 products for ion channel research, the listing includes research tools for the study of:

  • Ligand-gated ion channels
  • Voltage-gated ion channels
  • Other Ion Channels
Pain Research Product Guide

Pain Research Product Guide

A collection of over 280 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Epilepsy Poster

Epilepsy Poster

Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.

Pain Poster

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

Schizophrenia Poster

Schizophrenia Poster

Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.