Potent PI 3-Kγ, PI 3-Kα and PI 4-KIIIβ inhibitor (IC50 values are 16, 39 and 19 nM, respectively). Rescues PI 3K inhibition of growth of S. cerevisiae in a reverse halo assay.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 389.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.56 mL||12.82 mL||25.65 mL|
|5 mM||0.51 mL||2.56 mL||5.13 mL|
|10 mM||0.26 mL||1.28 mL||2.56 mL|
|50 mM||0.05 mL||0.26 mL||0.51 mL|
References are publications that support the biological activity of the product.
Burke et al (2014) Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab1 1 and its effectors. Science 344 1035 PMID: 24876499
Zunder et al (2008) Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 α. Cancer Cell 14 180 PMID: 18691552
Knight et al (2006) A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling. Cell 125 733 PMID: 16647110
If you know of a relevant reference for PIK 93, please let us know.
View Related Products by Product Action
Keywords: PIK 93, PIK 93 supplier, PIK93, Potent, PI, 3-Kgamma, 3-Kalpha, 4-KIIIbeta, inhibitors, inhibits, phosphoinositide, 3-kinase, 4-kinase, γ, β, α, 3-Kinase, Other, Kinases, 6440, Tocris Bioscience
Citations for PIK 93
Citations are publications that use Tocris products.
Currently there are no citations for PIK 93. Do you know of a great paper that uses PIK 93 from Tocris? Please let us know.
Reviews for PIK 93
There are currently no reviews for this product. Be the first to review PIK 93 and earn rewards!
Have you used PIK 93?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.