Phenobarbital sodium salt

Discontinued Product

Phenobarbital sodium salt (Cat. No. 4578) has been withdrawn from sale for commercial reasons.
Cat.No. 4578 - Phenobarbital sodium salt | C12H11N2NaO3 | CAS No. 57-30-7
Description: Enhances GABAergic activity
Chemical Name: 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Datasheet
Citations
Reviews
Literature

Biological Activity

Enhances GABAergic activity. Long-acting barbiturate; slow-acting barbiturate (Cat. No. 4579) also available.

Technical Data

M. Wt 254.22
Formula C12H11N2NaO3
Storage Store at RT
CAS Number 57-30-7
PubChem ID 12598276
InChI Key WRLGYAWRGXKSKG-UHFFFAOYSA-M
Smiles [Na+].CCC1(C(=O)NC([O-])=NC1=O)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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References

References are publications that support the biological activity of the product.

Nardou et al (2011) Phenobarbital but not diazepam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus. Front.Cell.Neurosci. 5 Epub PMID: 21847371

ffrench-Mullen et al (1993) Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. J.Neurosci. 13 3211 PMID: 8101867

Keywords: Phenobarbital sodium salt, Phenobarbital sodium salt supplier, Phenobarbital, barbiturates, anticonvulsants, GABAergic, GABA, Miscellaneous, GABAB, Receptors, 4578, Tocris Bioscience

Citations for Phenobarbital sodium salt

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.