Pentobarbital sodium salt

Pricing Availability Delivery Time Qty
Cat.No. 4579 - Pentobarbital sodium salt | C11H17N2NaO3 | CAS No. 57-33-0
Description: Enhances GABAergic activity
Chemical Name: 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Datasheet
Citations (1)
Literature

Biological Activity

Enhances GABAergic activity. Short-acting barbiturate; long-acting barbiturate (Cat. No. 4578) also available.

Technical Data

M. Wt 248.25
Formula C11H17N2NaO3
Storage Store at RT
CAS Number 57-33-0
PubChem ID 14075609
InChI Key QGMRQYFBGABWDR-UHFFFAOYSA-M
Smiles [Na+].CCCC(C)C1(CC)C(=O)NC([O-])=NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 24.82 100

Preparing Stock Solutions

The following data is based on the product molecular weight 248.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.14 mL 40.28 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.4 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.4 mL 0.81 mL

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Reconstitution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

Steinbach and Akk (2001) Modulation of GABAA receptor channel gating by pentobarbital. J.Physiol. 537 715 PMID: 11744750


If you know of a relevant reference for Pentobarbital sodium salt, please let us know.

Keywords: Pentobarbital sodium salt, supplier, Pentobarbital, barbiturates, hypnotics, anticonvulsants, GABAergic, GABA, Miscellaneous, GABA, Tocris Bioscience

1 Citation for Pentobarbital sodium salt

Citations are publications that use Tocris products. Selected citations for Pentobarbital sodium salt include:

Yan et al (2016) MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Nat Commun 38 201 PMID: 27247228


Do you know of a great paper that uses Pentobarbital sodium salt from Tocris? If so please let us know.

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Reviews

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Literature in this Area

GABA Receptors

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Pathways for Pentobarbital sodium salt

Protocols

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