Pentobarbital sodium salt

Pricing Availability   Qty
Description: Enhances GABAergic activity
Chemical Name: 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Citations (1)
Literature (1)

Biological Activity for Pentobarbital sodium salt

Pentobarbital sodium salt enhances GABAergic activity. Pentobarbital is a short-acting barbiturate.

Technical Data for Pentobarbital sodium salt

M. Wt 248.25
Formula C11H17N2NaO3
Storage Store at RT
CAS Number 57-33-0
PubChem ID 14075609
Smiles [Na+].CCCC(C)C1(CC)C(=O)NC([O-])=NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Pentobarbital sodium salt

Solvent Max Conc. mg/mL Max Conc. mM
water 24.82 100

Preparing Stock Solutions for Pentobarbital sodium salt

The following data is based on the product molecular weight 248.25. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.03 mL 20.14 mL 40.28 mL
5 mM 0.81 mL 4.03 mL 8.06 mL
10 mM 0.4 mL 2.01 mL 4.03 mL
50 mM 0.08 mL 0.4 mL 0.81 mL

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Product Datasheets for Pentobarbital sodium salt

Certificate of Analysis is currently unavailable on-line.
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References for Pentobarbital sodium salt

References are publications that support the biological activity of the product.

Steinbach and Akk (2001) Modulation of GABAA receptor channel gating by pentobar. J.Physiol. 537 715 PMID: 11744750

If you know of a relevant reference for Pentobarbital sodium salt, please let us know.

Keywords: Pentobarbital sodium salt, Pentobarbital sodium salt supplier, Pentobarbital, barbiturates, hypnotics, anticonvulsants, GABAergic, GABA, Miscellaneous, GABAB, Receptors, 4579, Tocris Bioscience

1 Citation for Pentobarbital sodium salt

Citations are publications that use Tocris products. Selected citations for Pentobarbital sodium salt include:

Yan et al (2016) MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Nat Commun 38 201 PMID: 27247228

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.