Pentobarbital sodium salt

Discontinued Product

Pentobarbital sodium salt (Cat. No. 4579) has been withdrawn from sale for commercial reasons.
Description: Enhances GABAergic activity
Chemical Name: 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Citations (6)
Literature (1)

Biological Activity for Pentobarbital sodium salt

Pentobarbital sodium salt enhances GABAergic activity. Pentobarbital is a short-acting barbiturate.

Technical Data for Pentobarbital sodium salt

M. Wt 248.25
Formula C11H17N2NaO3
Storage Store at RT
CAS Number 57-33-0
PubChem ID 14075609
Smiles [Na+].CCCC(C)C1(CC)C(=O)NC([O-])=NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Pentobarbital sodium salt

Certificate of Analysis is currently unavailable on-line.
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References for Pentobarbital sodium salt

References are publications that support the biological activity of the product.

Steinbach and Akk (2001) Modulation of GABAA receptor channel gating by pentobar. J.Physiol. 537 715 PMID: 11744750

Keywords: Pentobarbital sodium salt, Pentobarbital sodium salt supplier, Pentobarbital, barbiturates, hypnotics, anticonvulsants, GABAergic, GABA, Miscellaneous, GABAB, Receptors, 4579, Tocris Bioscience

6 Citations for Pentobarbital sodium salt

Citations are publications that use Tocris products. Selected citations for Pentobarbital sodium salt include:

Xueyu et al (2023) Upregulation of miR-144-3p alleviates Doxorubicin-induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis. Chem Biol Drug Des 101 24-39 PMID: 35730258

Jost B et al (2023) Intravitreal Short-Hairpin RNA Attenuated Adeno-Associated Virus-Induced Knockdown of Amphiregulin and Axial Elongation in Experimental Myopia. Invest Ophthalmol Vis Sci 64 11 PMID: 37040096

Ying et al (2021) The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization. J Cell Mol Med 25 6709-6720 PMID: 34057287

Jost B et al (2021) In vivo Imaging of Retina and Choroid in Guinea Pigs. Front Med (Lausanne) 8 730494 PMID: 34926491

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.