Pentobarbital sodium salt
Enhances GABAergic activity. Short-acting barbiturate; long-acting barbiturate (Cat. No. 4578) also available.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 248.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.03 mL||20.14 mL||40.28 mL|
|5 mM||0.81 mL||4.03 mL||8.06 mL|
|10 mM||0.4 mL||2.01 mL||4.03 mL|
|50 mM||0.08 mL||0.4 mL||0.81 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Steinbach and Akk (2001) Modulation of GABAA receptor channel gating by pentobarbital. J.Physiol. 537 715 PMID: 11744750
If you know of a relevant reference for Pentobarbital sodium salt, please let us know.
Keywords: Pentobarbital sodium salt, supplier, Pentobarbital, barbiturates, hypnotics, anticonvulsants, GABAergic, GABA, Miscellaneous, GABA, Tocris Bioscience
1 Citation for Pentobarbital sodium salt
Citations are publications that use Tocris products. Selected citations for Pentobarbital sodium salt include:
Yan et al (2016) MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Nat Commun 38 201 PMID: 27247228
Do you know of a great paper that uses Pentobarbital sodium salt from Tocris? If so please let us know.
Literature in this Area
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.