pCPA methyl ester hydrochloride

Pricing Availability   Qty

Save up to 40% on RUO Reagents with BIOSPRING24 (see details)

Description: Tryptophan hydroxylase inhibitor
Chemical Name: 4-Chloro-DL-Phenylalanine methyl ester hydrochloride
Purity: ≥98% (HPLC)

Biological Activity for pCPA methyl ester hydrochloride

pCPA methyl ester hydrochloride is a tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).

Compound Libraries for pCPA methyl ester hydrochloride

pCPA methyl ester hydrochloride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for pCPA methyl ester hydrochloride

M. Wt 250.12
Formula C10H12ClNO2.HCl
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 14173-40-1
PubChem ID 26531
Smiles O=C(C(CC1=CC=C(C=C1)Cl)N)OC.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for pCPA methyl ester hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
water 25.01 100
DMSO 25.01 100

Preparing Stock Solutions for pCPA methyl ester hydrochloride

The following data is based on the product molecular weight 250.12. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4 mL 19.99 mL 39.98 mL
5 mM 0.8 mL 4 mL 8 mL
10 mM 0.4 mL 2 mL 4 mL
50 mM 0.08 mL 0.4 mL 0.8 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets for pCPA methyl ester hydrochloride

Certificate of Analysis / Product Datasheet
Select another batch:

References for pCPA methyl ester hydrochloride

References are publications that support the biological activity of the product.

Pinto Brod et al (2016) Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test. Prog.Neuropsychopharmacol.Biol.Psychiatry. 65 201 PMID: 26596986

Wallace et al (2014) Vort. restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats. Int.J.Neuropsychopharmacol. 17 1695 PMID: 24852131

If you know of a relevant reference for pCPA methyl ester hydrochloride, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Hydroxylase Inhibitors

Keywords: pCPA methyl ester hydrochloride, pCPA methyl ester hydrochloride supplier, tryptophan, hydroxylase, inhibitors, inhibits, serotonin, 5-HT, depletion, depletes, synthesis, Hydroxylases, 5871, Tocris Bioscience

Citations for pCPA methyl ester hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for pCPA methyl ester hydrochloride. Do you know of a great paper that uses pCPA methyl ester hydrochloride from Tocris? Please let us know.

Reviews for pCPA methyl ester hydrochloride

There are currently no reviews for this product. Be the first to review pCPA methyl ester hydrochloride and earn rewards!

Have you used pCPA methyl ester hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review