pCPA methyl ester hydrochloride
Tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 250.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4 mL||19.99 mL||39.98 mL|
|5 mM||0.8 mL||4 mL||8 mL|
|10 mM||0.4 mL||2 mL||4 mL|
|50 mM||0.08 mL||0.4 mL||0.8 mL|
References are publications that support the products' biological activity.
Pinto Brod et al (2016) Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test. Prog.Neuropsychopharmacol.Biol.Psychiatry. 65 201 PMID: 26596986
Wallace et al (2014) Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats. Int.J.Neuropsychopharmacol. 17 1695 PMID: 24852131
If you know of a relevant reference for pCPA methyl ester hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: pCPA methyl ester hydrochloride, supplier, tryptophan, hydroxylase, inhibitors, inhibits, serotonin, 5-HT, depletion, depletes, synthesis, Hydroxylases, Hydroxylases, Tocris Bioscience
Citations for pCPA methyl ester hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for pCPA methyl ester hydrochloride. Do you know of a great paper that uses pCPA methyl ester hydrochloride from Tocris? If so please let us know.
Reviews for pCPA methyl ester hydrochloride
There are currently no reviews for this product. Be the first to review pCPA methyl ester hydrochloride and earn rewards!
Have you used pCPA methyl ester hydrochloride?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Spring/Summer 2018)New
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells