Binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 10 mM in 1eq. NaOH and to 5 mM in water with gentle warming|
References are publications that support the biological activity of the product.
Datla and Curzon (1996) Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats. Neuropharmacology 35 315 PMID: 8783206
Koyuncuoglu et al (1975) The effects of DL-p-chlorophenylalanine and DL-α-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat. Psychopharmacologia 45 163 PMID: 129787
If you know of a relevant reference for p-Chlorophenylalanine, please let us know.
View Related Products by Product Action
Keywords: p-Chlorophenylalanine, p-Chlorophenylalanine supplier, Tryptophan, hydroxylases, inhibitors, inhibits, serotonin, depletion, PCPA, fenclonine, 5-HT-Related, Hydroxylases, 5-HT3, Receptors, 0938, Tocris Bioscience
2 Citations for p-Chlorophenylalanine
Citations are publications that use Tocris products. Selected citations for p-Chlorophenylalanine include:
Hernandez et al (2012) Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals. Proc Natl Acad Sci U S A 302 E1009 PMID: 22318950
Tullius et al (2014) NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat Commun 5 5101 PMID: 25290058
Do you know of a great paper that uses p-Chlorophenylalanine from Tocris? Please let us know.
Reviews for p-Chlorophenylalanine
There are currently no reviews for this product. Be the first to review p-Chlorophenylalanine and earn rewards!
Have you used p-Chlorophenylalanine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)New
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells