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Submit ReviewNPEC-caged-LY 379268
Description: Caged version of LY 379268 (Cat. No. 2453)
Chemical Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
Biological Activity
NPEC ((N)-1-(2-Nitrophenyl)ethoxycarbonyl) caged version of LY 379268 (Cat.No. 2453), selective group II mGlu receptor agonist.
Technical Data
| M. Wt | 380.31 |
| Formula | C16H16N2O9 |
| Storage | Store at -20°C |
| InChI Key | AHJQYZMYVTZSGT-SZVKZECXSA-N |
| Smiles | O=C(N[C@]2([C@@](O)=O)[C@@]([C@H]3[C@](O)=O)([H])[C@@]3([H])OC2)OC(C1=C([N+]([O-])=O)C=CC=C1)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 38.03 | 100 | |
| DMSO | 38.03 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 380.31. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.63 mL | 13.15 mL | 26.29 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.63 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
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References
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