NocII

Pricing Availability Delivery Time Qty
Cat.No. 1119 - NocII | Phe-Ser-Glu-Phe-Met-Arg-Gln-Tyr-Leu-Val-Leu-Ser-Met-Gln-Ser-Ser-Gln | CAS No. 188119-47-3
Description: Orphan neuropeptide
Datasheet
Citations (1)
Literature

Biological Activity

Orphan neuropeptide, flanking nociceptin in the precursor pronociceptin. Stimulates locomotion in mice, possibly through a novel specific receptor.

Technical Data

M. Wt 2081.4
Formula C92H141N23O28S2
Sequence FSEFMRQYLVLSMQSSQ
Storage Desiccate at -20°C
CAS Number 188119-47-3
PubChem ID 90479756
InChI Key PPKKOTLGXBHLAB-XVHSACDVSA-N
Smiles [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2081.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.48 mL 2.4 mL 4.8 mL
5 mM 0.1 mL 0.48 mL 0.96 mL
10 mM 0.05 mL 0.24 mL 0.48 mL
50 mM 0.01 mL 0.05 mL 0.1 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet

References

References are publications that support the products' biological activity.

Florin et al (1997) Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. NeuroReport 8 705 PMID: 9106751

Florin et al (1999) Comparison of behavioural effects of NocII or NocIII, two related pronociceptin-derived peptides. Life Sci. 65 2727 PMID: 10622282


If you know of a relevant reference for NocII, please let us know.

View Related Products by Target

Keywords: NocII, supplier, Orphan, neuropeptide, Nociceptin, Receptors, ORL1, OP4, NOP, Opioid, neuropeptides, NOP, Receptors, NOP, Receptors, Tocris Bioscience

1 Citation for NocII

Citations are publications that use Tocris products. Selected citations for NocII include:

Laudenbach et al (2001) Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain. J Clin Invest 107 457 PMID: 11181645


Do you know of a great paper that uses NocII from Tocris? If so please let us know.

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