Home / Cell Biology / Stem Cells / Stem Cell Reprogramming / Neurodazine

Neurodazine

Cat. No. 3656 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Cat.No. 3656 - Neurodazine | C27H21ClN2O3 | CAS No. 937807-66-4
Description: Induces neurogenesis in mature skeletal muscle cells
Chemical Name: 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (4)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for Neurodazine

Neurodazine is an induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.

Technical Data for Neurodazine

M. Wt 456.92
Formula C27H21ClN2O3
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 937807-66-4
PubChem ID 16112820
InChI Key FEEOFPAEDSMOTO-UHFFFAOYSA-N
Smiles ClC1=CC=CC(C(O3)=CC=C3C2=NC(C5=CC=C(OC)C=C5)=C(C4=CC=C(OC)C=C4)N2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Neurodazine

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.69 100
ethanol 22.85 50

Preparing Stock Solutions for Neurodazine

The following data is based on the product molecular weight 456.92. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.19 mL 10.94 mL 21.89 mL
5 mM 0.44 mL 2.19 mL 4.38 mL
10 mM 0.22 mL 1.09 mL 2.19 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References for Neurodazine

References are publications that support the biological activity of the product.

Williams et al (2007) Synthetic small molecules that induce neurogenesis in skeletal muscle. J.Am.Chem.Soc. 129 9258 PMID: 17622149

Halder et al (2015) Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons. Chem.Biol. 22 1512 PMID: 26590637

If you know of a relevant reference for Neurodazine, please let us know.

View Related Products by Target

Keywords: Neurodazine, Neurodazine supplier, Neurodazine, stem, cells, neurogenesis, mature, human, skeletal, muscle, C2C12, myoblasts, neurogenics, Stem, Cell, Reprogramming, 3656, Tocris Bioscience

Citations for Neurodazine

Citations are publications that use Tocris products.

Currently there are no citations for Neurodazine. Do you know of a great paper that uses Neurodazine from Tocris? Please let us know.

Reviews for Neurodazine

There are currently no reviews for this product. Be the first to review Neurodazine and earn rewards!

Have you used Neurodazine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Stem Cell Research Product Guide

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells Scientific Review

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow Poster

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells Poster

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.