Pricing Availability   Qty
Description: Induces neurogenesis in mature skeletal muscle cells
Chemical Name: 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for Neurodazine

Neurodazine is an induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.

Technical Data for Neurodazine

M. Wt 456.92
Formula C27H21ClN2O3
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 937807-66-4
PubChem ID 16112820
Smiles ClC1=CC=CC(C(O3)=CC=C3C2=NC(C5=CC=C(OC)C=C5)=C(C4=CC=C(OC)C=C4)N2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Neurodazine

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 45.69 100
ethanol 22.85 50

Preparing Stock Solutions for Neurodazine

The following data is based on the product molecular weight 456.92. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.19 mL 10.94 mL 21.89 mL
5 mM 0.44 mL 2.19 mL 4.38 mL
10 mM 0.22 mL 1.09 mL 2.19 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

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References for Neurodazine

References are publications that support the biological activity of the product.

Williams et al (2007) Synthetic small molecules that induce neurogenesis in skeletal muscle. J.Am.Chem.Soc. 129 9258 PMID: 17622149

Halder et al (2015) Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons. Chem.Biol. 22 1512 PMID: 26590637

If you know of a relevant reference for Neurodazine, please let us know.

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Keywords: Neurodazine, Neurodazine supplier, Neurodazine, stem, cells, neurogenesis, mature, human, skeletal, muscle, C2C12, myoblasts, neurogenics, Stem, Cell, Reprogramming, 3656, Tocris Bioscience

Citations for Neurodazine

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Literature in this Area

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