N-MPPP Hydrochloride

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Cat.No. 0783 - N-MPPP Hydrochloride | C21H26N2O.HCl | CAS No. 207452-97-9
Description: Selective κ agonist
Chemical Name: N-Methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]phenylacetamide hydrochloride
Literature (5)

Biological Activity

High affinity κ agonist with no measured binding at μ or δ sites.

Technical Data

M. Wt 358.91
Formula C21H26N2O.HCl
Storage Store at RT
CAS Number 207452-97-9
PubChem ID 56972158
Smiles O=C(CC3=CC=CC=C3)N([C@]([C@]2=CC=CC=C2)([H])CN1CCCC1)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 8.97 25

Preparing Stock Solutions

The following data is based on the product molecular weight 358.91. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 11.14 mL 55.72 mL 111.45 mL
1.25 mM 2.23 mL 11.14 mL 22.29 mL
2.5 mM 1.11 mL 5.57 mL 11.14 mL
12.5 mM 0.22 mL 1.11 mL 2.23 mL

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Product Datasheets

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References are publications that support the biological activity of the product.

Weerawarna et al (1994) Isothiocyanate-substituted κ-selective opioid receptor ligands derived from N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]phenylacetamide. J.Med.Chem. 37 2856 PMID: 8071934

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Citations for N-MPPP Hydrochloride

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