Myelin Basic Protein (87-99)

Pricing Availability   Qty
Description: Major antigenic component implicated in the pathophysiology of multiple sclerosis
Purity: ≥95% (HPLC)

Biological Activity for Myelin Basic Protein (87-99)

Myelin Basic Protein (87-99) is an encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Major antigenic component implicated in the pathophysiology of multiple sclerosis.

Technical Data for Myelin Basic Protein (87-99)

M. Wt 1555.8
Formula C74H114N20O17
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 118506-26-6
PubChem ID 25077562
Smiles [H]N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Myelin Basic Protein (87-99)

Solubility Soluble to 2 mg/ml in water

Product Datasheets for Myelin Basic Protein (87-99)

Certificate of Analysis / Product Datasheet
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References for Myelin Basic Protein (87-99)

References are publications that support the biological activity of the product.

Jones et al (1992) The synthetic 87-99 peptide of myelin basic protein is encelphalitogenic in Buffalo rats. J.Neuroimmunol. 37 203 PMID: 1373154

Deraos et al (2008) Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP87-99) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: Implications in triggering disease. J.Med.Chem. 51 7834 PMID: 19053745

Hofstetter et al (2005) Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J.Immunol. 22 4598

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Keywords: Myelin Basic Protein (87-99), Myelin Basic Protein (87-99) supplier, antigenic, component, implicated, pathophysiology, multiple, sclerosis, Encephalitogenic, peptide, Neuronal, Metabolism, Miscellaneous, Compounds, 3399, Tocris Bioscience

Citations for Myelin Basic Protein (87-99)

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