Mometasone furoate

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Cat.No. 4115 - Mometasone furoate | C27H30Cl2O6 | CAS No. 83919-23-7
Description: Synthetic corticosteroid; anti-inflammatory agent
Chemical Name: 11β,16α)-9,21-Dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl 2-furoate
Purity: ≥99% (HPLC)
Literature (5)

Biological Activity for Mometasone furoate

Mometasone furoate is a potent synthetic corticosteroid; displays agonist activity at glucocorticoid and progesterone receptors. Exhibits anti-inflammatory effects.

Technical Data for Mometasone furoate

M. Wt 521.43
Formula C27H30Cl2O6
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 83919-23-7
PubChem ID 441336
Smiles O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@@](Cl)2[C@@H](O)C[C@@]4(C)[C@]([H])3C[C@@H](C)[C@@](OC(C5=CC=CO5)=O)4[C@@](CCl)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Mometasone furoate

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 52.14 100
ethanol 5.21 10

Preparing Stock Solutions for Mometasone furoate

The following data is based on the product molecular weight 521.43. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.92 mL 9.59 mL 19.18 mL
5 mM 0.38 mL 1.92 mL 3.84 mL
10 mM 0.19 mL 0.96 mL 1.92 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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Product Datasheets for Mometasone furoate

References for Mometasone furoate

References are publications that support the biological activity of the product.

Austin et al (2002) Mometasone furoate is a less specific glucocorticoid than flutic. propionate. Eur.Respir.J. 20 1386 PMID: 12503693

Ogawa et al (2009) Dissociation of local anti-inflammatory effect and systemic effects of momet. furoate in mice. Immunopharmacol.Immunotoxicol. 31 601 PMID: 19874229

If you know of a relevant reference for Mometasone furoate, please let us know.

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Keywords: Mometasone furoate, Mometasone furoate supplier, glucocorticoid, receptors, agonists, corticosteroids, anti-inflammatory, Glucocorticoid, Receptor, Progesterone, 4115, Tocris Bioscience

Citations for Mometasone furoate

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