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Potent synthetic corticosteroid; displays agonist activity at glucocorticoid and progesterone receptors. Exhibits anti-inflammatory effects.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 521.43. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.92 mL||9.59 mL||19.18 mL|
|5 mM||0.38 mL||1.92 mL||3.84 mL|
|10 mM||0.19 mL||0.96 mL||1.92 mL|
|50 mM||0.04 mL||0.19 mL||0.38 mL|
References are publications that support the biological activity of the product.
Austin et al (2002) Mometasone furoate is a less specific glucocorticoid than flutic. propionate. Eur.Respir.J. 20 1386 PMID: 12503693
Ogawa et al (2009) Dissociation of local anti-inflammatory effect and systemic effects of momet. furoate in mice. Immunopharmacol.Immunotoxicol. 31 601 PMID: 19874229
If you know of a relevant reference for Mometasone furoate, please let us know.
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Keywords: Mometasone furoate, Mometasone furoate supplier, glucocorticoid, receptors, agonists, corticosteroids, anti-inflammatory, Glucocorticoid, Receptor, Progesterone, 4115, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.