MLCK inhibitor peptide

Discontinued Product

MLCK inhibitor peptide (Cat. No. 1926) has been withdrawn from sale for commercial reasons.
Cat.No. 1926 - MLCK inhibitor peptide | Lys-Arg-Arg-Trp-Lys-Lys-Asn-Phe-Ile-Ala-Val-NH2 | CAS No. 198694-74-5
Description: Myosin light chain kinase inhibitor
Alternative Names: Myosin Light Chain Kinase Inhibitor
Datasheet
Citations
Reviews
Literature

Biological Activity

Competitive myosin light chain kinase (MLCK) inhibitor (Ki = 1 - 2.2 mM); derived from the calmodulin binding site of skeletal muscle MLCK. Also inhibits calmodulin.

Technical Data

M. Wt 1444.79
Formula C68H113N23O12
Sequence KRRWKKNFIAV

(Modifications: Val-11 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 198694-74-5
Smiles [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Kemp et al (1987) The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence. J.Biol.Chem. 262 2542 PMID: 3818608

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Keywords: MLCK inhibitor peptide, MLCK inhibitor peptide supplier, Myosin, light, chain, kinases, inhibitors, inhibits, MLCK, Light, Chain, Kinase, Inhibitor, Calcium, Binding, Protein, 1926, Tocris Bioscience

Citations for MLCK inhibitor peptide

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