You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
High affinity, partial agonist with a Ki value of 4.4 nM in rat brain.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 373.92. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||5.35 mL||26.74 mL||53.49 mL|
|2.5 mM||1.07 mL||5.35 mL||10.7 mL|
|5 mM||0.53 mL||2.67 mL||5.35 mL|
|25 mM||0.11 mL||0.53 mL||1.07 mL|
References are publications that support the biological activity of the product.
Damaj et al (1997) Pharmacology of lobeline, a nicotinic receptor ligand. J.Pharmacol.Exp.Ther. 282 410 PMID: 9223582
Merck Index 12 5580
Farook et al (2009) Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice. Physiol.Behav. 97 503 PMID: 19268674
If you know of a relevant reference for (-)-Lobeline hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: (-)-Lobeline hydrochloride, (-)-Lobeline hydrochloride supplier, Nicotinic, agonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, partial, (Non-selective), 1077, Tocris Bioscience
Citations for (-)-Lobeline hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for (-)-Lobeline hydrochloride. Do you know of a great paper that uses (-)-Lobeline hydrochloride from Tocris? Please let us know.
Reviews for (-)-Lobeline hydrochloride
There are currently no reviews for this product. Be the first to review (-)-Lobeline hydrochloride and earn rewards!
Have you used (-)-Lobeline hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.