Miconazole nitrate

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Cat.No. 3016 - Miconazole nitrate | C18H14Cl4N2O.HNO3 | CAS No. 22832-87-7
Description: Antifungal agent
Chemical Name: 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate
Purity: ≥99% (HPLC)

Biological Activity

Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species.

Compound Libraries

Miconazole nitrate is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 479.14
Formula C18H14Cl4N2O.HNO3
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 22832-87-7
PubChem ID 68553
Smiles ClC1=CC(Cl)=CC=C1COC(CN3C=CN=C3)C2=CC=C(Cl)C=C2Cl.O[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 47.91 100
ethanol 4.79 10

Preparing Stock Solutions

The following data is based on the product molecular weight 479.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.09 mL 10.44 mL 20.87 mL
5 mM 0.42 mL 2.09 mL 4.17 mL
10 mM 0.21 mL 1.04 mL 2.09 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Chang et al (2005) Effect of miconazole on intracellular Ca2+ levels and proliferation in human osteosarcoma cells. Life Sci. 76 2091 PMID: 15826876

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Keywords: Miconazole nitrate, supplier, Antifungal, agent, Miscellaneous, Compounds, Miscellaneous, Compounds, Tocris Bioscience

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