You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species. Enhances the generation of mature oligodendrocytes from progenitor cells in vitro and promotes myelination in vivo. Attenuates disease severity in a mouse model of multiple sclerosis. Brain penetrant.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 479.14. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.09 mL||10.44 mL||20.87 mL|
|5 mM||0.42 mL||2.09 mL||4.17 mL|
|10 mM||0.21 mL||1.04 mL||2.09 mL|
|50 mM||0.04 mL||0.21 mL||0.42 mL|
References are publications that support the biological activity of the product.
Chang et al (2005) Effect of miconazole on intracellular Ca2+ levels and proliferation in human osteosarcoma cells. Life Sci. 76 2091 PMID: 15826876
Najim et al (2015) Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature 522 216 PMID: 25896324
Hubler et al (2018) Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. Nature 560 372 PMID: 30046109
If you know of a relevant reference for Miconazole nitrate, please let us know.
Keywords: Miconazole nitrate, Miconazole nitrate supplier, Antifungal, agent, promotes, myelination, lanosterol, demethylase, inhibits, inhibitors, brain, penetrant, oligodendrocyte, differentiation, Other, Differentiation, Products, Antifungals, 3016, Tocris Bioscience
Citations for Miconazole nitrate
Citations are publications that use Tocris products.
Currently there are no citations for Miconazole nitrate. Do you know of a great paper that uses Miconazole nitrate from Tocris? Please let us know.
Reviews for Miconazole nitrate
There are currently no reviews for this product. Be the first to review Miconazole nitrate and earn rewards!
Have you used Miconazole nitrate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.