Mephedrone hydrochloride

Discontinued Product

Mephedrone hydrochloride (Cat. No. 4443) has been withdrawn from sale for commercial reasons.
Cat.No. 4443 - Mephedrone hydrochloride | C11H15NO.HCl | CAS No. 1189726-22-4
Description: Inhibits synaptosomal dopamine and 5-HT uptake
Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)propan-1-one hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Inhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.

Technical Data

M. Wt 213.7
Formula C11H15NO.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 1189726-22-4
PubChem ID 46782120
InChI Key DLQZFTUKJGRPLZ-UHFFFAOYSA-N
Smiles CC1=CC=C(C(C(C)NC)=O)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Hadlock et al (2011) 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J.Pharmacol.Exp.Ther. 339 530 PMID: 21810934

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Citations for Mephedrone hydrochloride

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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