MCOPPB trihydrochloride

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Cat.No. 3763 - MCOPPB trihydrochloride | C26H40N4.3HCl | CAS No. 1108147-88-1
Description: Potent NOP receptor agonist
Chemical Name: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole trihydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (5)

Biological Activity

High affinity NOP receptor agonist (pKi = 10.07 for the human NOP receptor). Exhibits anxiolytic effects with no effect on memory or locomotion. Regarded as one of the most potent, non-peptide NOP full agonists in vitro.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M. Wt 534.05
Formula C26H40N4.3HCl
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 1108147-88-1
PubChem ID 25208093
InChI Key DTIPEVOPCGEULQ-RFCADEKQSA-N
Smiles CC5(CCCCCCC5)N(CC4)CCC4N2C1=CC=CC=C1N=[C@@]2[C@H]3CNCCC3.Cl.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 16.02 30
DMSO 32.04 60

Preparing Stock Solutions

The following data is based on the product molecular weight 534.05. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.6 mM 3.12 mL 15.6 mL 31.21 mL
3 mM 0.62 mL 3.12 mL 6.24 mL
6 mM 0.31 mL 1.56 mL 3.12 mL
30 mM 0.06 mL 0.31 mL 0.62 mL

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