Lys-γ3-MSH

Pricing Availability Delivery Time Qty
Cat.No. 3611 - Lys-gamma3-MSH | Lys-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-Arg-Arg-Asn-Ser-Ser-Ser-Ser-Gly-Ser-Ser-Gly-Ala-Gly-Gln | CAS No. 156159-18-1
Description: Pro-opiomelanocortin (POMC) derived peptide
Datasheet
Citations
Literature

Biological Activity

Pro-opiomelanocortin (POMC) derived peptide. Potentiates the steriodogenic action of corticotrophin on the adrenal cortex, possibly via the MC3 receptor. Potently stimulates lipolysis via activation of hormone-sensitive lipase (HSL).

Technical Data

M. Wt 3018.27
Formula C128H193N45O39S
Sequence KYVMGHFRWDRFGRRNSSSSGSSGAGQ
Storage Store at -20°C
CAS Number 156159-18-1
PubChem ID 90488867
InChI Key XWFHPHMLENMPDT-KLQUGMGCSA-N
Smiles [H]N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in 10% acetonitrile / water

Preparing Stock Solutions

The following data is based on the product molecular weight 3018.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.33 mL 1.66 mL 3.31 mL
5 mM 0.07 mL 0.33 mL 0.66 mL
10 mM 0.03 mL 0.17 mL 0.33 mL
50 mM 0.01 mL 0.03 mL 0.07 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Harmer et al (2008) Evidence of a possible role fo Lys-γ3-MSH in the regulation of adipocyte function. J.Endocrinol. 196 149 PMID: 18180326

Bicknell et al (2009) Lys-gamma3-MSH: a global regulator of hormone-sensitive lipase activity? Mol.Cell.Endocrinol. 300 71 PMID: 18977407

Harmer and Bicknell (2004) The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal. Endocrine Res. 30 629 PMID:


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Keywords: Lys-gamma3-MSH, supplier, Pro-opiomelanocortin, POMC, hormone-sensitive, lipase, activators, HSL, melanocortin, receptors, Hydrolases, Lys-γ3-MSH, Lys-gamma3-MSH, Lys-γ3-Melanocyte-stimulating, Lys-gamma3-Melanocyte-stimulating, hormone, Melanocortin, Receptors, Other, Hydrolases, Melanocortin, Receptors, Tocris Bioscience

Citations for Lys-γ3-MSH

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Pathways for Lys-γ3-MSH

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