PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 358.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.79 mL||13.95 mL||27.9 mL|
|5 mM||0.56 mL||2.79 mL||5.58 mL|
|10 mM||0.28 mL||1.4 mL||2.79 mL|
|50 mM||0.06 mL||0.28 mL||0.56 mL|
References are publications that support the biological activity of the product.
Morrison et al (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 110 326 PMID: 26854431
If you know of a relevant reference for LTURM 36, please let us know.
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Keywords: LTURM 36, LTURM 36 supplier, LTURM36, PI3K, PI-3K, phosphoinositide, 3-kinases, inhibits, inhibitors, PI, 3-Kinase, 5835, Tocris Bioscience
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