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Submit ReviewLTURM 36 is a PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.
M. Wt | 358.39 |
Formula | C22H18N2O3 |
Storage | Store at +4°C |
Purity | ≥98% (HPLC) |
CAS Number | 1879887-94-1 |
PubChem ID | 122705988 |
InChI Key | HSONTPGVHUWDEY-UHFFFAOYSA-N |
Smiles | O=C1C2=C(C(C3=CC=CC4=C3C=CC=C4)=CC=C2)OC(N5CCOCC5)=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Morrison et al (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 110 326 PMID: 26854431
Keywords: LTURM 36, LTURM 36 supplier, LTURM36, PI3K, PI-3K, phosphoinositide, 3-kinases, inhibits, inhibitors, PI, 3-Kinase, 5835, Tocris Bioscience
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