Discontinued Product

LTURM 36 (Cat. No. 5835) has been withdrawn from sale for commercial reasons.
Description: PI 3-kinase δ inhibitor
Chemical Name: 2-(4-Morpholinyl)-8-(1-naphthalenyl)-4H-1,3-benzoxazin-4-one
Purity: ≥98% (HPLC)

Biological Activity for LTURM 36

LTURM 36 is a PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.

Technical Data for LTURM 36

M. Wt 358.39
Formula C22H18N2O3
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 1879887-94-1
PubChem ID 122705988
Smiles O=C1C2=C(C(C3=CC=CC4=C3C=CC=C4)=CC=C2)OC(N5CCOCC5)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for LTURM 36

References are publications that support the biological activity of the product.

Morrison et al (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 110 326 PMID: 26854431

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Keywords: LTURM 36, LTURM 36 supplier, LTURM36, PI3K, PI-3K, phosphoinositide, 3-kinases, inhibits, inhibitors, PI, 3-Kinase, 5835, Tocris Bioscience

Citations for LTURM 36

Citations are publications that use Tocris products.

Currently there are no citations for LTURM 36.

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