You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 11 nM). Inhibits p60c-src with an IC50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC50 > 100 μM).
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 381.38. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||10.49 mL||52.44 mL||104.88 mL|
|1.25 mM||2.1 mL||10.49 mL||20.98 mL|
|2.5 mM||1.05 mL||5.24 mL||10.49 mL|
|12.5 mM||0.21 mL||1.05 mL||2.1 mL|
References are publications that support the biological activity of the product.
Hsu et al (1991) Kinetic analysis of the inhibition of the epidermal growth factor receptor tyrosine kinase by lavendustin-A and its analogue. J.Biol.Chem. 266 21105 PMID: 1939153
O'Dell et al (1991) Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature 353 558 PMID: 1656271
Onoda et al (1989) Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus. J.Nat.Prod. 52 1252 PMID: 2614420
If you know of a relevant reference for Lavendustin A, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Lavendustin A, Lavendustin A supplier, EGFR, p60c-src, inhibitors, inhibits, Epidermal, Growth, Factors, Receptors, ErbB, Her, Receptor, Tyrosine, Kinases, RTKs, LavendustinA, RG14355, RG, 14355, Src, 1331, Tocris Bioscience
Citations for Lavendustin A
Citations are publications that use Tocris products.
Currently there are no citations for Lavendustin A. Do you know of a great paper that uses Lavendustin A from Tocris? Please let us know.
Reviews for Lavendustin A
There are currently no reviews for this product. Be the first to review Lavendustin A and earn rewards!
Have you used Lavendustin A?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.