HomoAMPA

Discontinued Product

HomoAMPA (Cat. No. 1026) has been withdrawn from sale for commercial reasons.
Description: Potent, highly selective mGlu6 agonist
Chemical Name: 2-Amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid
Datasheet
Citations
Reviews
Literature (3)

Biological Activity for HomoAMPA

The higher homolog of AMPA, this compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype-selective metabotropic glutamate receptor agonist.

Technical Data for HomoAMPA

M. Wt 200.19
Formula C8H12N2O4
Storage Store at RT
Smiles Cc1c(CCC(C(=O)O)N)c(no1)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for HomoAMPA

References are publications that support the biological activity of the product.

Brauner-Osbourne et al (1996) A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid. J.Med.Chem. 39 3188 PMID: 8759641

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Keywords: HomoAMPA, HomoAMPA supplier, Potent, selective, mGlu6, agonists, mGlur, Group, III, Receptors, mGluR6, Glutamate, Metabotropic, (Metabotropic), 1026, Tocris Bioscience

Citations for HomoAMPA

Citations are publications that use Tocris products.

Currently there are no citations for HomoAMPA.

Reviews for HomoAMPA

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.