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Biological Activity for HomoAMPA
The higher homolog of AMPA, this compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype-selective metabotropic glutamate receptor agonist.
Technical Data for HomoAMPA
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for HomoAMPA
References are publications that support the biological activity of the product.
Brauner-Osbourne et al (1996) A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid. J.Med.Chem. 39 3188 PMID: 8759641
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Keywords: HomoAMPA, HomoAMPA supplier, Potent, selective, mGlu6, agonists, mGlur, Group, III, Receptors, mGluR6, Glutamate, Metabotropic, (Metabotropic), 1026, Tocris Bioscience
Citations for HomoAMPA
Citations are publications that use Tocris products.
Currently there are no citations for HomoAMPA.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.