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Submit ReviewHomoAMPA
Discontinued Product
HomoAMPA (Cat. No. 1026) has been withdrawn from sale for commercial reasons.
Description: Potent, highly selective mGlu6 agonist
Chemical Name: 2-Amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid
Biological Activity for HomoAMPA
The higher homolog of AMPA, this compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype-selective metabotropic glutamate receptor agonist.
Technical Data for HomoAMPA
| M. Wt | 200.19 |
| Formula | C8H12N2O4 |
| Storage | Store at RT |
| Smiles | Cc1c(CCC(C(=O)O)N)c(no1)O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for HomoAMPA
References for HomoAMPA
References are publications that support the biological activity of the product.
Brauner-Osbourne et al (1996) A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid. J.Med.Chem. 39 3188 PMID: 8759641
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Keywords: HomoAMPA, HomoAMPA supplier, Potent, selective, mGlu6, agonists, mGlur, Group, III, Receptors, mGluR6, Glutamate, Metabotropic, (Metabotropic), 1026, Tocris Bioscience
Citations for HomoAMPA
Citations are publications that use Tocris products.
Currently there are no citations for HomoAMPA.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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