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Discontinued Product
HomoAMPA (Cat. No. 1026) has been withdrawn from sale for commercial reasons.
Description: Potent, highly selective mGlu6 agonist
Chemical Name: 2-Amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid
Biological Activity
The higher homolog of AMPA, this compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype-selective metabotropic glutamate receptor agonist.
Technical Data
| M. Wt | 200.19 |
| Formula | C8H12N2O4 |
| Storage | Store at RT |
| Smiles | Cc1c(CCC(C(=O)O)N)c(no1)O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Brauner-Osbourne et al (1996) A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid. J.Med.Chem. 39 3188 PMID: 8759641
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Keywords: HomoAMPA, HomoAMPA supplier, Potent, selective, mGlu6, agonists, mGlur, Group, III, Receptors, mGluR6, Glutamate, Metabotropic, (Metabotropic), 1026, Tocris Bioscience
Citations for HomoAMPA
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Currently there are no citations for HomoAMPA.
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*Please note that Tocris will only send literature to established scientific business / institute addresses.
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