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Biological Activity for GSK J2
GSK J2 is an inactive control of GSK J1 (IC50 > 100 μM for inhibition of JMJD3/UTX).
This compound is supplied in conjunction with the Structural Genomics Consortium. For further details of GSK J2, an inactive isomer of GSK J1, please visit the GSK J1 probe summary on the SGC website.
Technical Data for GSK J2
|Desiccate at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for GSK J2
|Max Conc. mg/mL
|Max Conc. mM
Preparing Stock Solutions for GSK J2
The following data is based on the product molecular weight 389.45. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass
References for GSK J2
References are publications that support the biological activity of the product.
Kruidenier et al (2012) A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488 404 PMID: 22842901
If you know of a relevant reference for GSK J2, please let us know.
View Related Products by Product Action
Keywords: GSK J2, GSK J2 supplier, GSKJ2, histone, demethylases, inhibitors, inhibits, UTX, JMJD3, KDM6, H3K27, epigenetics, Histone, Demethylases, 4688, Tocris Bioscience
Citations for GSK J2
Citations are publications that use Tocris products.
Currently there are no citations for GSK J2. Do you know of a great paper that uses GSK J2 from Tocris? Please let us know.
Reviews for GSK J2
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.