Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewGSK 9311 hydrochloride
Description: Negative control for GSK 6853
Chemical Name: N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxybenzamide hydrochloride
Purity: ≥98% (HPLC)
Biological Activity
Negative control for GSK 6853 (Cat. No. 6198)
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the GSK 9311 probe summary on the SGC website.
Compound Libraries
GSK 9311 hydrochloride is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 474 |
| Formula | C24H31N5O3.HCl |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 121232406 |
| InChI Key | WFXIHQFRQPGCCR-MRXNPFEDSA-N |
| Smiles | COC1=C(C(N(CC)C2=C(N3CCNC[C@H]3C)C=C4N(C(N(C4=C2)C)=O)C)=O)C=CC=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 47.4 | 100 | |
| DMSO | 47.4 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 474. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.11 mL | 10.55 mL | 21.1 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
| 10 mM | 0.21 mL | 1.05 mL | 2.11 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.42 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets
References
References are publications that support the biological activity of the product.
Bamborough et al (2016) GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain. ACS Med.Chem.Lett. 7 552 PMID: 27326325
If you know of a relevant reference for GSK 9311 hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: GSK 9311 hydrochloride, GSK 9311 hydrochloride supplier, GSK9311, HCl, BRPF1, inhibitors, negative, control, GSK, 6853, Bromodomains, 6203, Tocris Bioscience
Citations for GSK 9311 hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for GSK 9311 hydrochloride. Do you know of a great paper that uses GSK 9311 hydrochloride from Tocris? Please let us know.
Reviews for GSK 9311 hydrochloride
There are currently no reviews for this product. Be the first to review GSK 9311 hydrochloride and earn rewards!
Have you used GSK 9311 hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Research Product Guide
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Angiogenesis
- Invasion and Metastasis
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.
Epigenetics Research Bulletin
Produced by Tocris and updated in 2014, the epigenetics research bulletin gives an introduction into mechanisms of epigenetic regulation, and highlights key Tocris products for epigenetics targets including:
- Bromodomains
- DNA Methyltransferases
- Histone Deacetylases
- Histone Demethylases
- Histone Methyltransferases
Cell Cycle & DNA Damage Repair Poster
In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.