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Submit ReviewGSK 9311 hydrochloride
Description: Negative control for GSK 6853
Chemical Name: N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxybenzamide hydrochloride
Purity: ≥98% (HPLC)
Biological Activity
Negative control for GSK 6853 (Cat. No. 6198)
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the GSK 9311 probe summary on the SGC website.
Compound Libraries
GSK 9311 hydrochloride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 474 |
| Formula | C24H31N5O3.HCl |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| PubChem ID | 121232406 |
| InChI Key | WFXIHQFRQPGCCR-MRXNPFEDSA-N |
| Smiles | COC1=C(C(N(CC)C2=C(N3CCNC[C@H]3C)C=C4N(C(N(C4=C2)C)=O)C)=O)C=CC=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 47.4 | 100 | |
| DMSO | 47.4 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 474. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.11 mL | 10.55 mL | 21.1 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
| 10 mM | 0.21 mL | 1.05 mL | 2.11 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.42 mL |
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Product Datasheets
References
References are publications that support the biological activity of the product.
Bamborough et al (2016) GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain. ACS Med.Chem.Lett. 7 552 PMID: 27326325
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Citations for GSK 9311 hydrochloride
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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