GSK 9311 hydrochloride

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Description: Negative control for GSK 6853
Chemical Name: N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-N-ethyl-2-methoxybenzamide hydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (6)

Biological Activity for GSK 9311 hydrochloride

GSK 9311 hydrochloride is a negative control for GSK 6853 (Cat. No. 6198)

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the GSK 9311 probe summary on the SGC website.

Compound Libraries for GSK 9311 hydrochloride

GSK 9311 hydrochloride is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.

Technical Data for GSK 9311 hydrochloride

M. Wt 474
Formula C24H31N5O3.HCl
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 2253733-09-2
PubChem ID 121232406
InChI Key WFXIHQFRQPGCCR-MRXNPFEDSA-N
Smiles COC1=C(C(N(CC)C2=C(N3CCNC[C@H]3C)C=C4N(C(N(C4=C2)C)=O)C)=O)C=CC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for GSK 9311 hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 47.4 100
DMSO 47.4 100

Preparing Stock Solutions for GSK 9311 hydrochloride

The following data is based on the product molecular weight 474. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.11 mL 10.55 mL 21.1 mL
5 mM 0.42 mL 2.11 mL 4.22 mL
10 mM 0.21 mL 1.05 mL 2.11 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

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Product Datasheets for GSK 9311 hydrochloride

References for GSK 9311 hydrochloride

References are publications that support the biological activity of the product.

Bamborough et al (2016) GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain. ACS Med.Chem.Lett. 7 552 PMID: 27326325


If you know of a relevant reference for GSK 9311 hydrochloride, please let us know.

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Citations for GSK 9311 hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for GSK 9311 hydrochloride. Do you know of a great paper that uses GSK 9311 hydrochloride from Tocris? Please let us know.

Reviews for GSK 9311 hydrochloride

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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